Hi Rajeev,
My old replies are correct.
-----------------------------------------------------------------------------------------------------------------------------
1> Windows Backup of E:\usr\sap.
2> DB2 Database backup by logging into the Database via DB2<SID> User.
I don't know how to take DB2 Offline Backup.
3> Then, take System State backup which will take the registry backup.
-----------------------------------------------------------------------------------------------------------------------------
1) Take offline file system backup (e:) on windows and tape
2) Take DB backup on tapes may be offline
3) Take system state backup
4) Perofrm your activity
5) Restore only E: drive and start SAP.
-------------------------------------------------------------------------------------------------------------------------------
Last not the least; take help of SAP by raising an OSS if there is any doubt and the server is critical to you.
Regards
Kaushik Banerjee